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Brainnetome: A New Avenue to Understand the Brain and its Disorders

Tianzi Jiang
Brainnetome Center, Institute of Automation
Chinese Academy of Sciences, Beijing, 100190
China
and
National Laboratory of Pattern Recognition, Institute of Automation
Chinese Academy of Sciences, Beijing, 100190 China
and
Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia
and
Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology
University of Electronic Science and Technology of China, Chengdu, 610054, China

jiangtz@nlpr.ia.ac.cn

Abstract

The Brainnetome (Brain-net-ome) is a new "-ome" in which the brain network is its basic research unit. It includes at least the following essential components: network topological structure (connectome), performance, dynamics, manifestation of functions and malfunctions of brain on different scales, genetic basis of brain networks, and simulating and modeling brain networks on supercomputing facilities. Here we will review progress on some aspects of the Brannetome, including Brainnetome atlas, Brainnetome-wise Association Studies (BWAS) of neurological and psychiatric diseases, such as schizophrenia and Alzheimer’s disease, and how the Brainnetome meets genome, and so on. It envisions that the Brainnetome will become an emerging co-frontier of brain imaging, information technology, neurology and psychiatry. Some long-standing issues in neuropsychiatry may be solved by combining the Brainnetome with genome.

Short Bio

Tianzi Jiang is Professor of Brain Imaging and Cognitive Disorders, Institute Automation of Chinese Academy of Sciences (CASIA), and Professor of Queensland Brain Institute, University of Queensland. He is the Director of Brainnetome Center of CASIA and the Chinese Director of the Sino-French Laboratory in Computer Science, Automation and Applied Mathematics (LIAMA), one National Center for International Research. His research interests include neuroimaging, Brainnetome, imaging genetics, and their clinical applications in brain disorders and development. He is the author or co-author of over 200 reviewed journal papers in these fields and the co-editor of six issues of the Lecture Notes in Computer Sciences. He is Associate Editor of IEEE Transactions on Medical Imaging, IEEE Transactions on Autonomous Mental Development, Neuroscience Bulletin and an Academic Editor of PLoS One.


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